Metal Gear Solid V: The Phantom Pain has a rather huge game breaking glitch that can potentially wipe out your save data of the game. This glitch can occur under specific circumstances so it is not random at all, and hence it can be avoided.
If you are currently playing Metal Gear Solid V: The Phantom Pain and are using Quiet as a Buddy for missions. It is strongly recommended to avoid using her as Buddy for Mission 29 and Mission 42 until this game breaking glitch is patched.
This issue is confirmed to be present in PS3, PS4, Xbox 360, Xbox One and PC. If you are currently playing any of these missions and want to avoid getting your data corrupted, it is best to choose another buddy instead of Quiet for these specific missions.
Metal Gear Solid V: The Phantom Pain was released on September 1st for PS3, PS4, PC, Xbox 360 and Xbox One.
Let us know if you have experienced any issues with the game in the comments below.